The Age of Enlightenment (1650 CE – 1800 CE) introduced original modes of thinking about God, religion, and humanity’s spiritual relationship with nature. These illuminating ideas culminated in an ideology known as Deism which was primarily influenced by John Locke (1632 CE – 1704 CE). This paper focuses on events leading up to the formation of Deism and its five fundamental principles. Locke’s philosophy advanced theological discourse as a rational form of spiritual expression.