I’m not anti-vaxx, I just don’t trust American health agencies. Wouldn’t even think twice if this was in most other countries

  • Sulvor [he/him, undecided]@hexbear.netEnglish
    18·
    2 months ago

    Currently, over half of infections in the US are from the KP3 variant. The virus is mutating so fast our vaccine production is struggling to keep up. The current vaccines target KP2, which is closely related to KP3. These vaccines will better protect you against what is currently circulating compared to the vaccines we have had previously.

    • GaveUp [she/her]@hexbear.netOPEnglish
      4·
      2 months ago

      No yea I understand the reasoning behind why vaccines get updates. I meant like trial testing data for safety profile and what not

      • Sulvor [he/him, undecided]@hexbear.netEnglish
        12·
        2 months ago

        I believe these are the original ingredients from the first round. Pfizer changed which preservatives they use, but it appears the preservatives in the current Pfizer shot are what Moderna used originally. Besides that all they are changing is the specific mRNA sequence to encode for and target the new variants. In terms of safety, they are no different than what was approved in the original study.

        • GaveUp [she/her]@hexbear.netOPEnglish
          4·
          2 months ago

          In terms of safety, they are no different than what was approved in the original study.

          Has it been studied that changing the mRNA encoding doesn’t affect the safety? From my extremely limited understanding that shouldn’t be something that can just be assumed right?

          • Sulvor [he/him, undecided]@hexbear.netEnglish
            11·
            2 months ago

            All that is changing is the little piece of non-infectious and benign spike protein that your own ribosomes are producing, so that your immune system can identify it later. The mRNA sequence itself is only present for a couple days at most before it degrades and you no longer produce the spike proteins.

            And yes, even under the emergency use authorization, each new mRNA sequence is tested for safety and efficacy in animals and humans before release.

            The sequence could encode for millions of bits of viruses and other things that would all be non-harmful. The preservatives and other ingredients are what have caused serious events such as myocarditis, anaphylaxis, etc.

            I will try to find a meta analysis of a bunch of mRNA vaccines or a study on mRNA technology when I can.

            Basically though, it is impossible that changing the spike protein is gonna change anything except what your immune system learns.